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3vqt
From Proteopedia
Contents |
Crystal structure analysis of the translation factor RF3
Template:ABSTRACT PUBMED 22975312
Function
[RF3_DESVM] Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity).
About this Structure
3vqt is a 4 chain structure with sequence from Desulfovibrio vulgaris str. 'miyazaki f'. Full crystallographic information is available from OCA.
Reference
- Kihira K, Shimizu Y, Shomura Y, Shibata N, Kitamura M, Nakagawa A, Ueda T, Ochi K, Higuchi Y. Crystal structure analysis of the translation factor RF3 (release factor 3). FEBS Lett. 2012 Oct 19;586(20):3705-9. doi: 10.1016/j.febslet.2012.08.029. Epub, 2012 Sep 6. PMID:22975312 doi:10.1016/j.febslet.2012.08.029
