4ew3

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Template:STRUCTURE 4ew3

The structure of human glycinamide ribonucleotide transformylase in complex with 10R-methylthio-DDATHF.

Template:ABSTRACT PUBMED 23869564

About this Structure

4ew3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Connelly S, Demartino JK, Boger DL, Wilson IA. Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry. 2013 Jul 30;52(30):5133-44. doi: 10.1021/bi4005182. Epub 2013 Jul, 19. PMID:23869564 doi:10.1021/bi4005182

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