4iz6
From Proteopedia
Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry
Function
[ENTE_ECOLI] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine.
About this Structure
4iz6 is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Categories: Escherichia coli | Gulick, A M. | Sundlov, J A. | 4'phosphopantetheinylation cofactor 4'pp | Acyl carrier protein | Adenylate-forming enzyme | Anl superfamily | Chimera protein | Fusion protein | Ligase | Non-ribosomal peptide synthetase | Nrps adenylation domains and acyl carrier protein domain | Pseudo-translational symmetry
