4i74

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Template:STRUCTURE 4i74

Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion

Template:ABSTRACT PUBMED 16630632

About this Structure

4i74 is a 1 chain structure with sequence from Trypanosoma brucei brucei strain 927/4 gutat10.1. Full crystallographic information is available from OCA.

Reference

  • Versees W, Barlow J, Steyaert J. Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. J Mol Biol. 2006 Jun 2;359(2):331-46. Epub 2006 Mar 29. PMID:16630632 doi:10.1016/j.jmb.2006.03.026

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