4hna

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Template:STRUCTURE 4hna

Contents 1 Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN 2 Function 3 About this Structure 4 See Also 5 Reference

Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN

Template:ABSTRACT PUBMED 23872990

Function

[KINH_HUMAN] Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).

About this Structure

4hna is a 4 chain structure with sequence from Alfaropsis roxburghiana, Ovis aries and Synthetic construct. Full crystallographic information is available from OCA.

See Also

• Tubulin

Reference

• Gigant B, Wang W, Dreier B, Jiang Q, Pecqueur L, Pluckthun A, Wang C, Knossow M. Structure of a kinesin-tubulin complex and implications for kinesin motility. Nat Struct Mol Biol. 2013 Aug;20(8):1001-7. doi: 10.1038/nsmb.2624. Epub 2013 Jul, 21. PMID:23872990 doi:10.1038/nsmb.2624