4kjk

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Template:STRUCTURE 4kjk

Contents 1 Room Temperature WT DHFR 2 Function 3 About this Structure 4 Reference

Room Temperature WT DHFR

Template:ABSTRACT PUBMED 23913260

Function

[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

4kjk is a 1 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

• van den Bedem H, Bhabha G, Yang K, Wright PE, Fraser JS. Automated identification of functional dynamic contact networks from X-ray crystallography. Nat Methods. 2013 Aug 4. doi: 10.1038/nmeth.2592. PMID:23913260 doi:10.1038/nmeth.2592