User:Alice Harmon/Sandbox 2

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CDPK

Calcium-dependent protein kinases (CDPKs) are found in plants, algae, and apicomplexan protists, such as the parasites that cause malaria and toxoplasmosis. They comprise a protein kinase domain linked to a calcium-binding regulatory domain, and they belong to the calmodulin-dependent protein kinase family.

Crystal stuctures of inactive and active conformations of CDPK1 from 'Toxoplama gondii' show the dramatic conformation change that occurs upon the binding of calcium to the regulatory domain.

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Alice Harmon

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