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From Proteopedia
proteopedia linkproteopedia linkBcl-Xl is a member of the
Bcl-2 family . This family consists of pro-apoptotic and anti-apoptotic members. Bcl-Xl as
.an anti a poptotivc protein binds pro apoptotic proteins like BAK and BAD thus inhibiting program cell death. Many cancer cells overexpress at least one of the anti-apoptotic members of this family , thus escaping apoptosis . Therefore these proteins are important targets for the development of new anti-cancer drugs.
