4l4j

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Template:STRUCTURE 4l4j

Contents 1 Crystal structure of fc-fragment of human IgG2-Sigma antibody 2 Disease 3 About this Structure 4 Reference

Crystal structure of fc-fragment of human IgG2-Sigma antibody

Template:ABSTRACT PUBMED 23872058

Disease

[IGHG2_HUMAN] Recurrent infections associated with rare immunoglobulin isotypes deficiency.

About this Structure

4l4j is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Vafa O, Gilliland GL, Brezski RJ, Strake B, Wilkinson T, Lacy ER, Scallon B, Teplyakov A, Malia TJ, Strohl WR. An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations. Methods. 2013 Jul 17. pii: S1046-2023(13)00247-8. doi:, 10.1016/j.ymeth.2013.06.035. PMID:23872058 doi:10.1016/j.ymeth.2013.06.035