4j6p

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Template:STRUCTURE 4j6p

Contents

Crystal structure of calcium2+-free wild-type CD23 lectin domain (crystal form F)

Template:ABSTRACT PUBMED 23933509

Function

[FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

About this Structure

4j6p is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dhaliwal B, Pang MO, Yuan D, Yahya N, Fabiane SM, McDonnell JM, Gould HJ, Beavil AJ, Sutton BJ. Conformational plasticity at the IgE-binding site of the B-cell receptor CD23. Mol Immunol. 2013 Aug 6;56(4):693-697. doi: 10.1016/j.molimm.2013.07.005. PMID:23933509 doi:10.1016/j.molimm.2013.07.005

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OCA

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