3vwv

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Template:STRUCTURE 3vwv

Contents

crystal structure of N-terminally truncated peroxiredoxin 4 from M. musculus

Template:ABSTRACT PUBMED 23949117

Function

[PRDX4_MOUSE] Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

About this Structure

3vwv is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Sato Y, Kojima R, Okumura M, Hagiwara M, Masui S, Maegawa K, Saiki M, Horibe T, Suzuki M, Inaba K. Synergistic cooperation of PDI family members in peroxiredoxin 4-driven oxidative protein folding. Sci Rep. 2013 Aug 16;3:2456. doi: 10.1038/srep02456. PMID:23949117 doi:10.1038/srep02456

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