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4gv5

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Template:STRUCTURE 4gv5

X-ray structure of crotamine, a cell-penetrating peptide from the Brazilian snake Crotalus durissus terrificus

Function

[MYX_CRODR] This toxin specifically modifies voltage-gated sodium channels (Nav), it exhibits analgesic activity. Moreover, it actively interacts with lipid membranes (By similarity). It induces severe myonecrosis accompanied by edema and hemorrhage.

About this Structure

4gv5 is a 3 chain structure with sequence from Crotalus durissus ruruima. Full crystallographic information is available from OCA.

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