4kg8
From Proteopedia
Crystal structure of light mutant
Function
[TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
About this Structure
4kg8 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Categories: Homo sapiens | Almo, S C. | Bonanno, J B. | IFN, Atoms-to-Animals:.The Immune Function Network. | Kumar, P R. | Liu, W. | NYSGRC, New York Structural Genomics Research Consortium. | Nathenson, S G. | Zhan, C. | Atoms-to-animals: the immune function network | Bind tnf receptor hvem and ltbr | Cytokine | Dcr3 | Hvem | Ifn | Immunity | Jelly-roll fold | Ltbr | Membrane | N-glycosylation | New york structural genomics research consortium | Nysgrc | Protein structure initiative | Psi-biology | Secreted protein | Structural genomic | Tnf superfamily
