1jj9

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Template:STRUCTURE 1jj9

Contents 1 Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition 2 Function 3 About this Structure 4 See Also 5 Reference

Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition

Template:ABSTRACT PUBMED 11278347

Function

[MMP8_HUMAN] Can degrade fibrillar type I, II, and III collagens.

About this Structure

1jj9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Matrix metalloproteinase

Reference

• Brandstetter H, Grams F, Glitz D, Lang A, Huber R, Bode W, Krell HW, Engh RA. The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition. J Biol Chem. 2001 May 18;276(20):17405-12. Epub 2001 Jan 22. PMID:11278347 doi:10.1074/jbc.M007475200