3d9a

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Template:STRUCTURE 3d9a

Contents

High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme

Template:ABSTRACT PUBMED 19781789

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

About this Structure

3d9a is a 3 chain structure with sequence from Gallus gallus and Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  • Acchione M, Lipschultz CA, DeSantis ME, Shanmuganathan A, Li M, Wlodawer A, Tarasov S, Smith-Gill SJ. Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies. Mol Immunol. 2009 Dec;47(2-3):457-64. Epub 2009 Sep 24. PMID:19781789 doi:10.1016/j.molimm.2009.08.018
  1. Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

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