4kjz

From Proteopedia

Revision as of 06:51, 29 September 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4kjz

Contents

Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)

Template:ABSTRACT PUBMED 24029018

Function

[IF2_THET8] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).

About this Structure

4kjz is a 4 chain structure with sequence from Thermus thermophilus hb8. Full crystallographic information is available from OCA.

Reference

  • Eiler D, Lin J, Simonetti A, Klaholz BP, Steitz TA. Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15662-7. doi:, 10.1073/pnas.1309360110. Epub 2013 Sep 12. PMID:24029018 doi:10.1073/pnas.1309360110

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4kjz"
Personal tools