2r0l

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2r0l

Contents 1 Short Form HGFA with Inhibitory Fab75 2 Function 3 About this Structure 4 See Also 5 Reference

Short Form HGFA with Inhibitory Fab75

Template:ABSTRACT PUBMED 18077410

Function

[HGFA_HUMAN] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

About this Structure

2r0l is a 4 chain structure with sequence from [1], Homo sapiens and Ruellia. Full crystallographic information is available from OCA.

See Also

• Antibody

Reference

• Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. Epub 2007 Dec 5. PMID:18077410