3zf8
From Proteopedia
Contents |
Crystal structure of Saccharomyces cerevisiae Mnn9 in complex with GDP and Mn.
Template:ABSTRACT PUBMED 24026536
Function
[MNN9_YEAST] The M-Pol I and M-Pol II complexes possess alpha-1,6-mannosyltransferase activity and are probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins. May also provide alpha-1,2-mannosyltransferase activity to the M-Pol I complex.[1]
About this Structure
3zf8 is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
Reference
- Striebeck A, Robinson DA, Schuttelkopf AW, van Aalten DM. Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis. Open Biol. 2013 Sep 11;3(9):130022. doi: 10.1098/rsob.130022. PMID:24026536 doi:10.1098/rsob.130022
- ↑ Stolz J, Munro S. The components of the Saccharomyces cerevisiae mannosyltransferase complex M-Pol I have distinct functions in mannan synthesis. J Biol Chem. 2002 Nov 22;277(47):44801-8. Epub 2002 Sep 15. PMID:12235155 doi:10.1074/jbc.M208023200
