4h2a
From Proteopedia
Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)
Function
[PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
About this Structure
4h2a is a 1 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.
