4m4w

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Template:STRUCTURE 4m4w

Contents

Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex

Template:ABSTRACT PUBMED 24048025

Function

[DNAI_BACSU] Probably involved in DNA replication. [PRIM_GEOSE] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.

About this Structure

4m4w is a 15 chain structure with sequence from Bacillus subtilis subsp. subtilis str. 168 and Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

  • Liu B, Eliason WK, Steitz TA. Structure of a helicase-helicase loader complex reveals insights into the mechanism of bacterial primosome assembly. Nat Commun. 2013;4:2495. doi: 10.1038/ncomms3495. PMID:24048025 doi:10.1038/ncomms3495

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OCA

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