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2kw6
From Proteopedia
Contents |
Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H
Template:ABSTRACT PUBMED 22427660
Function
[CDKA1_HUMAN] specific inhibitor of the cell-cycle kinase CDK2 (By similarity).
About this Structure
2kw6 is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, Maglaqui M, Lee HW, Prestegard JH, Montelione GT. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region. J Biol Chem. 2012 May 11;287(20):16541-9. Epub 2012 Mar 14. PMID:22427660 doi:10.1074/jbc.M112.343863
Categories: Homo sapiens | Acton, T B. | Aramini, J M. | Ciccosanti, C T. | Ertekin, A. | Everett, J K. | Jiang, M. | Lee, A B. | Montelione, G T. | NESG, Northeast Structural Genomics Consortium. | Prestegard, J H. | Rossi, P. | Rost, B. | Swapna, G V.T. | Xiao, R. | Cancer suppressor | Cell cycle | Protein structure initiative | Psi-2 | Structural genomic
