4glr

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Template:STRUCTURE 4glr

Structure of the anti-ptau Fab (pT231/pS235_1) in complex with phosphoepitope pT231/pS235

Template:ABSTRACT PUBMED 23148212

About this Structure

4glr is a 6 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Shih HH, Tu C, Cao W, Klein A, Ramsey R, Fennell BJ, Lambert M, Ni Shuilleabhain D, Autin B, Kouranova E, Laxmanan S, Braithwaite S, Wu L, Ait-Zahra M, Milici AJ, Dumin JA, Lavallie ER, Arai M, Corcoran C, Paulsen JE, Gill D, Cunningham O, Bard J, Mosyak L, Finlay WJ. An Ultra-specific Avian Antibody to Phosphorylated Tau Protein Reveals a Unique Mechanism for Phosphoepitope Recognition. J Biol Chem. 2012 Dec 28;287(53):44425-34. doi: 10.1074/jbc.M112.415935. Epub, 2012 Nov 12. PMID:23148212 doi:10.1074/jbc.M112.415935

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