4lfp
From Proteopedia
Contents |
X-ray structure of the adduct between hen egg white lysozyme and a homoleptic gold(I) complex with the saccharynate ligand
Template:ABSTRACT PUBMED 24045294
Function
[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]
About this Structure
4lfp is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.
Reference
- Messori L, Scaletti F, Massai L, Cinellu MA, Gabbiani C, Vergara A, Merlino A. The mode of action of anticancer gold-based drugs: a structural perspective. Chem Commun (Camb). 2013 Sep 18. PMID:24045294 doi:10.1039/c3cc46400h
- ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021