This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4hp2
From Proteopedia
Contents |
Invariom refinement of a new dimeric monoclinic 2 solvate of thiostrepton at 0.64 angstrom resolution
Template:ABSTRACT PUBMED 23897476
Function
[THCL_STRAJ] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity).
About this Structure
4hp2 is a 2 chain structure with sequence from Streptomyces azureus. Full crystallographic information is available from OCA.
Reference
- Propper K, Holstein JJ, Hubschle CB, Bond CS, Dittrich B. Invariom refinement of a new monoclinic solvate of thiostrepton at 0.64 A resolution. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1530-9. doi:, 10.1107/S0907444913010664. Epub 2013 Jul 19. PMID:23897476 doi:10.1107/S0907444913010664
