3v8h

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Template:STRUCTURE 3v8h

Contents 1 Crystal structure of Thymidylate Synthase from Burkholderia thailandensis 2 Function 3 About this Structure 4 See Also 5 Reference

Crystal structure of Thymidylate Synthase from Burkholderia thailandensis

Template:ABSTRACT PUBMED 23382856

Function

[Q2SXY2_BURTA] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).[HAMAP-Rule:MF_00008]

About this Structure

3v8h is a 4 chain structure with sequence from Burkholderia thailandensis e264. Full crystallographic information is available from OCA.

See Also

• Thymidylate synthase

Reference

• Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC. Combining functional and structural genomics to sample the essential Burkholderia structome. PLoS One. 2013;8(1):e53851. doi: 10.1371/journal.pone.0053851. Epub 2013 Jan 31. PMID:23382856 doi:http://dx.doi.org/10.1371/journal.pone.0053851