4c13

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Template:STRUCTURE 4c13

Contents

x-ray crystal structure of Staphylococcus aureus MurE with UDP-MurNAc- Ala-Glu-Lys

Template:ABSTRACT PUBMED 24064214

Function

[D4U2M7_STAAU] Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity).[HAMAP-Rule:MF_00208]

About this Structure

4c13 is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Ruane KM, Lloyd AJ, Fulop V, Dowson CG, Barreteau H, Boniface A, Dementin S, Blanot D, Mengin-Lecreulx D, Gobec S, Dessen A, Roper DI. Specificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Ternary Complex. J Biol Chem. 2013 Sep 24. PMID:24064214 doi:http://dx.doi.org/10.1074/jbc.M113.508135

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