4bmc

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Template:STRUCTURE 4bmc

Contents

Crystal structure of s.pombe Rad4 BRCT1,2

Template:ABSTRACT PUBMED 24074952

Function

[RAD4_SCHPO] Essential component for DNA replication and also the checkpoint control system which couples S and M phases. May directly or indirectly interact with chromatin proteins to form the complex required for the initiation and/or progression of DNA synthesis.

About this Structure

4bmc is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

  • Qu M, Rappas M, Wardlaw CP, Garcia V, Ren JY, Day M, Carr AM, Oliver AW, Du LL, Pearl LH. Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(TopBP1.). Mol Cell. 2013 Sep 26;51(6):723-36. doi: 10.1016/j.molcel.2013.08.030. PMID:24074952 doi:http://dx.doi.org/10.1016/j.molcel.2013.08.030

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OCA

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