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This Sandbox is Reserved from Oct 10, 2013, through May 20, 2014 for use in the course "CHEM 410 Biochemistry 1 and 2" taught by Hanna Tims at the Messiah College. This reservation includes Sandbox Reserved 780 through Sandbox Reserved 807.

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Contents 1 Glyceraldehyde-3-phosphate dehydrogenase 1.1 Introduction and Basic Structure 1.2 Bonding 1.3 Residues 1.4 Solvent 1.5 Ligands and Ligand Contacts 1.6 Resources

Glyceraldehyde-3-phosphate dehydrogenase

Introduction and Basic Structure

spinqualitylabelsall models Glyceraldehyde-3-phosphate dehydrogenase Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Glyceraldehyde-3-phosphate dehydrogenase, or more commonly called, , is a tetrahedral protein. G-3-P is an enzyme used in glycolysis to produce NADH through a mechanism with phosphate and NAD+, which binds to the ligand binding site of G-3-P. The has both alpha helices (purple) and beta sheets (green). The shows a more accurate representation of what this enzyme looks like.

Bonding

The are colored in orange. Based on the amount of the thin orange lines, it is made clear that there are many hydrogen bonds. However, there are no within the structure, or they would have been highlighted in green. The only special binding in the G-3-P enzyme is the hydrogen bonding. Looking at the structure with the highlights the structure of the beta sheets. Looking at the image, it seems that the beta sheets are both parallel and anti-parallel in structure.

Residues

The are shown in grey. The are shown in royal blue. The hydrophobic residues are on the internal part of the enzyme while the hydrophilic sections surround the hydrophobic residues.

Solvent

Ligands and Ligand Contacts

Resources