3m6m

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Template:STRUCTURE 3m6m

Contents 1 Crystal structure of RpfF complexed with REC domain of RpfC 2 Function 3 About this Structure 4 See Also 5 Reference

Crystal structure of RpfF complexed with REC domain of RpfC

Template:ABSTRACT PUBMED 20826346

Function

[RPFC_XANCP] Member of the two-component regulatory system RpfG/RpfC, which is required for full virulence and for formation and dispersal of biofilms. Involved in sensing and responding to the diffusible signaling factor (DSF), which is essential for cell-cell signaling. RpfC is probably a sensor of environmental signals, including DSF, which is autophosphorylated at a histidine residue in response to the signal. Then, probably activates RpfG via a four-step phosphorelay. May also negatively regulate the production of DSF, independently of RpfG (By similarity).

About this Structure

3m6m is a 6 chain structure with sequence from Xanthomonas campestris pv. campestris. Full crystallographic information is available from OCA.

See Also

• Response regulator

Reference

• Cheng Z, He YW, Lim SC, Qamra R, Walsh MA, Zhang LH, Song H. Structural basis of the sensor-synthase interaction in autoinduction of the quorum sensing signal DSF biosynthesis. Structure. 2010 Sep 8;18(9):1199-209. PMID:20826346 doi:10.1016/j.str.2010.06.011