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2rs7

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Revision as of 06:52, 16 October 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 2rs7

Contents

Solution structure of the second dsRBD from RNA helicase A

Template:ABSTRACT PUBMED 22454253

Function

[DHX9_MOUSE] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).

About this Structure

2rs7 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.

Reference

  • Nagata T, Tsuda K, Kobayashi N, Shirouzu M, Kigawa T, Guntert P, Yokoyama S, Muto Y. Solution structures of the double-stranded RNA-binding domains from RNA helicase A. Proteins. 2012 Jun;80(6):1699-706. doi: 10.1002/prot.24059. Epub 2012 Mar 27. PMID:22454253 doi:http://dx.doi.org/10.1002/prot.24059

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OCA

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