4lt6

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Template:STRUCTURE 4lt6

Contents

Crystal Structure of human poly(A) polymerase gamma

Template:ABSTRACT PUBMED 24076191

Function

[PAPOG_HUMAN] Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA.

About this Structure

4lt6 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yang Q, Nausch L, Martin G, Keller W, Doublie S. Crystal Structure of Human Poly(A) Polymerase Gamma Reveals a Conserved Catalytic Core for Canonical Poly(A) Polymerases. J Mol Biol. 2013 Sep 25. pii: S0022-2836(13)00609-8. doi:, 10.1016/j.jmb.2013.09.025. PMID:24076191 doi:http://dx.doi.org/10.1016/j.jmb.2013.09.025

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OCA

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