4bwd

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Template:STRUCTURE 4bwd

Contents 1 Human short coiled coil protein 2 Function 3 About this Structure 4 Reference

Human short coiled coil protein

Template:ABSTRACT PUBMED 24098481

Function

[SCOC_HUMAN] Positive regulator of amino acid starvation-induced autophagy.^[1]

About this Structure

4bwd is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Behrens C, Binotti B, Schmidt C, Robinson CV, Chua JJ, Kuhnel K. Crystal Structure of the Human Short Coiled Coil Protein and Insights into SCOC-FEZ1 Complex Formation. PLoS One. 2013 Oct 1;8(10):e76355. PMID:24098481 doi:http://dx.doi.org/10.1371/journal.pone.0076355

1. ↑ McKnight NC, Jefferies HB, Alemu EA, Saunders RE, Howell M, Johansen T, Tooze SA. Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC. EMBO J. 2012 Apr 18;31(8):1931-46. doi: 10.1038/emboj.2012.36. Epub 2012 Feb 21. PMID:22354037 doi:10.1038/emboj.2012.36