4ih1

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Template:STRUCTURE 4ih1

Contents 1 Crystal structure of Karrikin Insensitive 2 (KAI2) from Arabidopsis thaliana 2 Function 3 About this Structure 4 Reference

Crystal structure of Karrikin Insensitive 2 (KAI2) from Arabidopsis thaliana

Function

[KAI2_ARATH] Involved in seed germination and seedling development. Essential for plant responses to karrikins, a class of butenolide compounds, structurally similar to strigolactones, released from burning vegetation that stimulate seed germination and enhance seedling photomorphogenesis. KAI2 is not required for strigolactone-mediated responses, but MAX2 is necessary for responses to karrikins and strigolactones.^{[1] [2] [3] [4]}

About this Structure

4ih1 is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

• Zhao LH, Zhou XE, Wu ZS, Yi W, Xu Y, Li S, Xu TH, Liu Y, Chen RZ, Kovach A, Kang Y, Hou L, He Y, Xie C, Song W, Zhong D, Xu Y, Wang Y, Li J, Zhang C, Melcher K, Xu HE. Crystal structures of two phytohormone signal-transducing alpha/beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res. 2013 Mar;23(3):436-9. doi: 10.1038/cr.2013.19. Epub 2013 Feb 5. PMID:23381136 doi:http://dx.doi.org/10.1038/cr.2013.19

1. ↑ Sun XD, Ni M. HYPOSENSITIVE TO LIGHT, an alpha/beta fold protein, acts downstream of ELONGATED HYPOCOTYL 5 to regulate seedling de-etiolation. Mol Plant. 2011 Jan;4(1):116-26. doi: 10.1093/mp/ssq055. Epub 2010 Sep 23. PMID:20864454 doi:10.1093/mp/ssq055
2. ↑ Waters MT, Nelson DC, Scaffidi A, Flematti GR, Sun YK, Dixon KW, Smith SM. Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis. Development. 2012 Apr;139(7):1285-95. doi: 10.1242/dev.074567. Epub 2012 Feb 22. PMID:22357928 doi:10.1242/dev.074567
3. ↑ Waters MT, Smith SM. KAI2- and MAX2-mediated responses to karrikins and strigolactones are largely independent of HY5 in Arabidopsis seedlings. Mol Plant. 2013 Jan;6(1):63-75. doi: 10.1093/mp/sss127. Epub 2012 Nov 9. PMID:23142794 doi:10.1093/mp/sss127
4. ↑ Kagiyama M, Hirano Y, Mori T, Kim SY, Kyozuka J, Seto Y, Yamaguchi S, Hakoshima T. Structures of D14 and D14L in the strigolactone and karrikin signaling pathways. Genes Cells. 2013 Jan 10. doi: 10.1111/gtc.12025. PMID:23301669 doi:10.1111/gtc.12025