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4k90

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Template:STRUCTURE 4k90

Contents

Extracellular metalloproteinase from Aspergillus

Template:ABSTRACT PUBMED 24100314

Function

[ELM_ASPFU] Secreted metalloproteinase that allows assimilation of proteinaceous substrates and probably acts as a virulence factor (By similarity). Catalyzes the hydrolysis of elastin.

About this Structure

4k90 is a 2 chain structure with sequence from Aspergillus fumigatus af293 and Zasmidium angulare. Full crystallographic information is available from OCA.

Reference

  • Fernandez D, Russi S, Vendrell J, Monod M, Pallares I. A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus. Acta Crystallogr D Biol Crystallogr. 2013 Oct;69(Pt 10):1946-57. doi:, 10.1107/S0907444913017642. Epub 2013 Sep 20. PMID:24100314 doi:http://dx.doi.org/10.1107/S0907444913017642

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OCA

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