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1vvk

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Revision as of 06:48, 23 October 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 1vvk

Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex (SecYEBeta + 50S ribosomal proteins)

Function

[SECY_METJA] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. [SECG_METJA] Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. [SECE_METJA] Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

About this Structure

1vvk is a 9 chain structure with sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.

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