4khw

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Template:STRUCTURE 4khw

Contents

Ternary complex of RB69 mutant L415F with ribonucleotide at -2 position

Template:ABSTRACT PUBMED 24082122

Function

[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.

About this Structure

4khw is a 3 chain structure with sequence from Enterobacteria phage rb69. Full crystallographic information is available from OCA.

Reference

  • Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA. Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16802-7. doi:, 10.1073/pnas.1309119110. Epub 2013 Sep 30. PMID:24082122 doi:http://dx.doi.org/10.1073/pnas.1309119110

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OCA

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