4ghk

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Template:STRUCTURE 4ghk

Contents

X-ray Crystal Structure of Gamma-glutamyl phosphate reductase from Burkholderia thailandensis

Template:ABSTRACT PUBMED 23382856

Function

[PROA_BURTA] Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity).

About this Structure

4ghk is a 4 chain structure with sequence from Burkholderia thailandensis e264. Full crystallographic information is available from OCA.

Reference

  • Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC. Combining functional and structural genomics to sample the essential Burkholderia structome. PLoS One. 2013;8(1):e53851. doi: 10.1371/journal.pone.0053851. Epub 2013 Jan 31. PMID:23382856 doi:http://dx.doi.org/10.1371/journal.pone.0053851

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OCA

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