4knn

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Template:STRUCTURE 4knn

Contents 1 Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide 2 Function 3 About this Structure 4 Reference

Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide

Template:ABSTRACT PUBMED 24103428

Function

[CAH13_HUMAN] Reversible hydration of carbon dioxide.

About this Structure

4knn is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Capkauskaite E, Zubriene A, Smirnov A, Torresan J, Kisonaite M, Kazokaite J, Gylyte J, Michailoviene V, Jogaite V, Manakova E, Grazulis S, Tumkevicius S, Matulis D. Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII. Bioorg Med Chem. 2013 Nov 15;21(22):6937-47. doi: 10.1016/j.bmc.2013.09.029. Epub, 2013 Sep 20. PMID:24103428 doi:http://dx.doi.org/10.1016/j.bmc.2013.09.029