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4n96

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Revision as of 07:56, 6 November 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4n96

E. coli sliding clamp in complex with 6-nitroindazole

Function

[DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.

About this Structure

4n96 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

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