4m63

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Template:STRUCTURE 4m63

Contents 1 Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL 2 Function 3 About this Structure 4 Reference

Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL

Template:ABSTRACT PUBMED 24120140

Function

[ACT1_DROME] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.

About this Structure

4m63 is a 5 chain structure with sequence from Drome and Vibrio parahaemolyticus bb22op. Full crystallographic information is available from OCA.

Reference

• Zahm JA, Padrick SB, Chen Z, Pak CW, Yunus AA, Henry L, Tomchick DR, Chen Z, Rosen MK. The Bacterial Effector VopL Organizes Actin into Filament-like Structures. Cell. 2013 Oct 10;155(2):423-34. doi: 10.1016/j.cell.2013.09.019. PMID:24120140 doi:http://dx.doi.org/10.1016/j.cell.2013.09.019