3i4o

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Template:STRUCTURE 3i4o

Contents

Crystal Structure of Translation Initiation Factor 1 from Mycobacterium tuberculosis

Template:ABSTRACT PUBMED 20132820

Function

[IF1_MYCTU] No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity).

About this Structure

3i4o is a 2 chain structure with sequence from Mycobacterium sp. h37rv. Full crystallographic information is available from OCA.

Reference

  • Hatzopoulos GN, Mueller-Dieckmann J. Structure of translation initiation factor 1 from Mycobacterium tuberculosis and inferred binding to the 30S ribosomal subunit. FEBS Lett. 2010 Mar 5;584(5):1011-5. Epub 2010 Feb 2. PMID:20132820 doi:10.1016/j.febslet.2010.01.051

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