4a5z

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Template:STRUCTURE 4a5z

Contents

Structures of MITD1

Template:ABSTRACT PUBMED 23045692

Function

[MITD1_HUMAN] Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex.[1] [2]

About this Structure

4a5z is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Hadders MA, Agromayor M, Obita T, Perisic O, Caballe A, Kloc M, Lamers MH, Williams RL, Martin-Serrano J. ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes. Proc Natl Acad Sci U S A. 2012 Oct 8. PMID:23045692 doi:http://dx.doi.org/10.1073/pnas.1206839109
  1. Lee S, Chang J, Renvoise B, Tipirneni A, Yang S, Blackstone C. MITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesis. Mol Biol Cell. 2012 Nov;23(22):4347-61. doi: 10.1091/mbc.E12-04-0292. Epub 2012, Sep 26. PMID:23015756 doi:http://dx.doi.org/10.1091/mbc.E12-04-0292
  2. Hadders MA, Agromayor M, Obita T, Perisic O, Caballe A, Kloc M, Lamers MH, Williams RL, Martin-Serrano J. ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes. Proc Natl Acad Sci U S A. 2012 Oct 8. PMID:23045692 doi:http://dx.doi.org/10.1073/pnas.1206839109

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