2maw
From Proteopedia
Contents |
NMR structures of the alpha7 nAChR transmembrane domain.
Disease
[ACHA7_HUMAN] 15q13.3 microdeletion syndrome.
Function
[ACHA7_HUMAN] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
About this Structure
2maw is a 1 chain structure. Full experimental information is available from OCA.
