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4lf3

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Template:STRUCTURE 4lf3

Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor

Function

[GLR_HUMAN] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

About this Structure

4lf3 is a 6 chain structure. Full crystallographic information is available from OCA.

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