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4m2p

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Template:STRUCTURE 4m2p

Contents

Crystal structure of a non-myristoylated C39D recoverin mutant with one calcium ion bound to EF-hand 3

Function

[RECO_BOVIN] Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.[1] [2]

About this Structure

4m2p is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Hurley JB, Dizhoor AM, Ray S, Stryer L. Recoverin's role: conclusion withdrawn. Science. 1993 May 7;260(5109):740. PMID:8097896
  2. ↑ Kawamura S, Hisatomi O, Kayada S, Tokunaga F, Kuo CH. Recoverin has S-modulin activity in frog rods. J Biol Chem. 1993 Jul 15;268(20):14579-82. PMID:8392055

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