4bza

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Template:STRUCTURE 4bza

Contents

Crystal structure of TamA POTRA domains 1-3 from E. coli

Template:ABSTRACT PUBMED 24056943

Function

[TAMA_ECOLI] Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane. Has anion selective channel-forming ability, but the physiological relevance of this activity is unclear.[1]

About this Structure

4bza is a 1 chain structure with sequence from Ecobd. Full crystallographic information is available from OCA.

Reference

  • Gruss F, Zahringer F, Jakob RP, Burmann BM, Hiller S, Maier T. The structural basis of autotransporter translocation by TamA. Nat Struct Mol Biol. 2013 Sep 22. doi: 10.1038/nsmb.2689. PMID:24056943 doi:10.1038/nsmb.2689
  1. ↑ Selkrig J, Mosbahi K, Webb CT, Belousoff MJ, Perry AJ, Wells TJ, Morris F, Leyton DL, Totsika M, Phan MD, Celik N, Kelly M, Oates C, Hartland EL, Robins-Browne RM, Ramarathinam SH, Purcell AW, Schembri MA, Strugnell RA, Henderson IR, Walker D, Lithgow T. Discovery of an archetypal protein transport system in bacterial outer membranes. Nat Struct Mol Biol. 2012 Apr 1;19(5):506-10, S1. doi: 10.1038/nsmb.2261. PMID:22466966 doi:10.1038/nsmb.2261

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