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3roa

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Revision as of 12:24, 20 November 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 3roa

Candida glabrata dihydrofolate reductase complexed with NADPH and 6-ethyl-5-[(3R)-3-[3-methoxy-5-(morpholin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP1004)

Template:ABSTRACT PUBMED 23375226

About this Structure

3roa is a 2 chain structure with sequence from Atcc 2001. Full crystallographic information is available from OCA.

Reference

  • Paulsen JL, Viswanathan K, Wright DL, Anderson AC. Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1279-84. doi: 10.1016/j.bmcl.2013.01.008. , Epub 2013 Jan 11. PMID:23375226 doi:http://dx.doi.org/10.1016/j.bmcl.2013.01.008

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OCA

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