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3qlr

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Revision as of 12:24, 20 November 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 3qlr

Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)

Template:ABSTRACT PUBMED 21726415

About this Structure

3qlr is a 2 chain structure with sequence from candida_stellatoidea Atcc 11006 candida stellatoidea. Full crystallographic information is available from OCA.

Reference

  • Paulsen JL, Bendel SD, Anderson AC. Crystal structures of Candida albicans dihydrofolate reductase bound to propargyl-linked antifolates reveal the flexibility of active site loop residues critical for ligand potency and selectivity. Chem Biol Drug Des. 2011 Jul 5. doi: 10.1111/j.1747-0285.2011.01169.x. PMID:21726415 doi:10.1111/j.1747-0285.2011.01169.x

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OCA

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