We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

4i18

From Proteopedia

Revision as of 13:42, 20 November 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4i18

Contents

Crystal structure of human prolactin receptor complexed with Fab fragment

Function

[PRLR_HUMAN] This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.[1]

About this Structure

4i18 is a 6 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Trott JF, Hovey RC, Koduri S, Vonderhaar BK. Alternative splicing to exon 11 of human prolactin receptor gene results in multiple isoforms including a secreted prolactin-binding protein. J Mol Endocrinol. 2003 Feb;30(1):31-47. PMID:12580759

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4i18"
Personal tools