4i79

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Template:STRUCTURE 4i79

Contents

Crystal structure of human NUP43

Function

[NUP43_HUMAN] Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.[1]

About this Structure

4i79 is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See Also

Reference

  1. ↑ Zuccolo M, Alves A, Galy V, Bolhy S, Formstecher E, Racine V, Sibarita JB, Fukagawa T, Shiekhattar R, Yen T, Doye V. The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions. EMBO J. 2007 Apr 4;26(7):1853-64. Epub 2007 Mar 15. PMID:17363900 doi:http://dx.doi.org/10.1038/sj.emboj.7601642

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